Open AccessWolbachia Infections in Aedes aegypti Differ Markedly in Their Response to Cyclical Heat Stress
Author(s) -
Perran A. Ross,
Itsanun Wiwatanaratanabutr,
Jason K. Axford,
Vanessa L. White,
Nancy M. EndersbyHarshman,
Ary A. Hoffmann
Publication year - 2017
Publication title -
plos pathogens
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.719
H-Index - 206
eISSN - 1553-7374
pISSN - 1553-7366
DOI - 10.1371/journal.ppat.1006006
Subject(s) - wolbachia , aedes aegypti , biology , cytoplasmic incompatibility , larva , aedes , vector (molecular biology) , zoology , virology , microbiology and biotechnology , ecology , host (biology) , genetics , gene , recombinant dna
Aedes aegypti mosquitoes infected with Wolbachia bacteria are currently being released for arbovirus suppression around the world. Their potential to invade populations and persist will depend on interactions with environmental conditions, particularly as larvae are often exposed to fluctuating and extreme temperatures in the field. We reared Ae . aegypti larvae infected with different types of Wolbachia ( w Mel, w AlbB and w MelPop-CLA) under diurnal cyclical temperatures. Rearing w Mel and w MelPop-CLA-infected larvae at 26–37°C reduced the expression of cytoplasmic incompatibility, a reproductive manipulation induced by Wolbachia . We also observed a sharp reduction in the density of Wolbachia in adults. Furthermore, the w Mel and w MelPop-CLA infections were not transmitted to the next generation when mosquitoes were exposed to 26–37°C across all life stages. In contrast, the w AlbB infection was maintained at a high density, exhibited complete cytoplasmic incompatibility, and was transmitted from mother to offspring with a high fidelity under this temperature cycle. These findings have implications for the potential success of Wolbachia interventions across different environments and highlight the importance of temperature control in rearing.