Open AccessAnnona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes
Author(s) -
Oluwafemi Adeleke Ojo,
Susan Grant,
Jennifer Chidubem Amanze,
Abosede Itunuoluwa Oni,
Adebola Busola Ojo,
Tobiloba Christiana Elebiyo,
Tajudeen Olabisi Obafemi,
Damilare Iyinkristi Ayokunle,
Akingbolabo Daniel Ogunlakin
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0276984
Subject(s) - downregulation and upregulation , pi3k/akt/mtor pathway , apoptosis , annona muricata , inflammation , protein kinase b , carbohydrate metabolism , enzyme , carbohydrate , biology , gene , chemistry , biochemistry , botany , immunology