Open AccessSelection of single domain anti-transferrin receptor antibodies for blood-brain barrier transcytosis using a neurotensin based assay and histological assessment of target engagement in a mouse model of Alzheimer’s related amyloid-beta pathology
Author(s) -
Shiran Su,
Thomas J. Esparza,
David L. Brody
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0276107
Subject(s) - transcytosis , transferrin receptor , single domain antibody , microbiology and biotechnology , mutant , blood–brain barrier , chemistry , antibody , receptor , biology , biochemistry , immunology , gene , endocytosis , neuroscience , central nervous system