Open AccessBayesian and frequentist approaches to sequential monitoring for futility in oncology basket trials: A comparison of Simon’s two-stage design and Bayesian predictive probability monitoring with information sharing across baskets
Author(s) -
Alexander M. Kaizer,
Emily C. Zabor,
Lei Nie,
Brian P. Hobbs
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0272367
Subject(s) - frequentist inference , bayesian probability , sample size determination , clinical trial , computer science , clinical study design , protocol (science) , bayes' theorem , statistical power , machine learning , medicine , medical physics , bayesian inference , artificial intelligence , statistics , mathematics , pathology , alternative medicine