Open AccessHuman iPSC-derived astrocytes generated from donors with globoid cell leukodystrophy display phenotypes associated with disease
Author(s) -
Richard Lieberman,
Leslie K. Cortes,
Grace Gao,
Hye-Jung Park,
Bing Wang,
Patrick L. Jones,
Robert B. Hunter,
John P. Leonard,
Robert H. Barker
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0271360
Subject(s) - krabbe disease , leukodystrophy , sphingolipid , biology , induced pluripotent stem cell , microglia , lysosomal storage disease , microbiology and biotechnology , metachromatic leukodystrophy , astrocyte , ceramide , neurodegeneration , immunology , disease , inflammation , neuroscience , pathology , medicine , central nervous system , genetics , biochemistry , enzyme , embryonic stem cell , gene , apoptosis
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