Open AccessNew compounds from heterocyclic amines scaffold with multitarget inhibitory activity on Aβ aggregation, AChE, and BACE1 in the Alzheimer disease
Author(s) -
Iohanan Daniel García Marín,
Raúl Horacio Camarillo López,
Oscar Aurelio Martínez,
Itzia I. PadillaMartínez,
José CorreaBasurto,
Martha Cecilia RosalesHernández
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0269129
Subject(s) - chemistry , pharmacophore , acetylcholinesterase , pyrrolidine , stereochemistry , amyloid beta , ic50 , amyloid precursor protein , biochemistry , in vitro , alzheimer's disease , enzyme , medicine , peptide , disease , pathology