Open AccessDeveloping predictive hybridization models for phosphorothioate oligonucleotides using high-resolution melting
Author(s) -
Siyuan S Wang,
Erhu Xiong,
Sanchita Bhadra,
Andrew D. Ellington
Publication year - 2022
Publication title -
plos one
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0268575
Subject(s) - oligonucleotide , nucleic acid , phosphodiester bond , duplex (building) , nucleic acid thermodynamics , dna , rational design , locked nucleic acid , chemistry , computational biology , combinatorial chemistry , rna , biophysics , biological system , biology , biochemistry , base sequence , genetics , gene