Open AccessA novel 3-acyl isoquinolin-1(2H)-one induces G2 phase arrest, apoptosis and GSDME-dependent pyroptosis in breast cancer
Author(s) -
Lei Ma,
Mengyao Bian,
Hui Gao,
Zhi Zhou,
Wei Yi
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0268060
Subject(s) - apoptosis , cell cycle , pyroptosis , cancer research , breast cancer , cell cycle checkpoint , cancer , viability assay , cancer cell , cyclin dependent kinase 1 , programmed cell death , cell growth , mcf 7 , chemistry , biology , biochemistry , genetics , human breast