Open AccessLeveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk
Author(s) -
Muhammad Ali,
Yun Ju Sung,
Fengxian Wang,
María Victoria Fernández,
John C. Morris,
Anne M. Fagan,
Kaj Blennow,
Henrik Zetterberg,
Amanda Heslegrave,
Per Johansson,
Johan Svensson,
Bengt Nellgård,
Alberto Lleó,
Daniel Alcolea,
Jordi Clarimón,
Lorena Rami,
José Luís Molinuevo,
Marc SuárezCalvet,
Estrella MorenasRodríguez,
Gernot Kleinberger,
Christian Haass,
Michael Ewers,
Johannes Levin,
Martin R. Farlow,
Richard J. Perrin,
Carlos Cruchaga
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0267298
Subject(s) - endophenotype , trem2 , biomarker , medicine , oncology , dementia , cerebrospinal fluid , odds ratio , neuroprotection , alzheimer's disease , clusterin , disease , pathology , bioinformatics , inflammation , biology , genetics , psychiatry , cognition , microglia , apoptosis