Open AccessReduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial hypocalciuric hypercalcemia type 1
Author(s) -
Xiaohua Wang,
James Lundblad,
Stephen M. Smith
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0266993
Subject(s) - calcium sensing receptor , receptor , mutant , hek 293 cells , mutation , wild type , transfection , chemistry , calcium in biology , extracellular , microbiology and biotechnology , biology , endocrinology , medicine , calcium , calcium metabolism , biochemistry , gene
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