Open AccessProhaptoglobin inhibits the transforming growth factor-β-induced epithelial-to-mesenchymal transition in vitro by increasing Smad1/5 activation and suppressing the Smad2/3 signaling pathway in SK-Hep1 liver cancer cells
Author(s) -
Mi-Kyung Oh,
Hansol Joo,
In-Sook Kim
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0266409
Subject(s) - epithelial–mesenchymal transition , smad , mesenchymal stem cell , microbiology and biotechnology , signal transduction , vimentin , phosphorylation , transforming growth factor , biology , transforming growth factor beta , cancer research , gene knockdown , downregulation and upregulation , chemistry , cell culture , immunology , biochemistry , immunohistochemistry , genetics , gene