Open AccessConstruction of sublingual trilaminated Eszopiclone fast dissolving film for the treatment of Insomnia: Formulation, characterization and In vivo clinical comparative pharmacokinetic study in healthy human subjects
Author(s) -
Mahmoud H. Teaima,
Mohamed Yasser,
Nehal Elfar,
Kamel R. Shoueir,
Mohamed A. El-Nabarawi,
Doaa A. Helal
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0266019
Subject(s) - in vivo , pharmacokinetics , polyvinyl alcohol , mannitol , dissolution , dissolution testing , folding endurance , pullulan , materials science , pharmacology , chemistry , medicine , biochemistry , composite material , organic chemistry , polysaccharide , biopharmaceutics classification system , microbiology and biotechnology , first pass effect , biology