Open AccessOral, genital and anal human papillomavirus infections among female sex workers in Ibadan, Nigeria
Author(s) -
Imran O. Morhason-Bello,
Guy Harling,
Miquel Ángel Pavón,
Isaac F. Adewole,
Rasheed Bakare,
Sílvia de Sanjosé,
Suzanna C. Francis,
Deborah Watson-Jones
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0265269
Subject(s) - medicine , concordance , anus , hpv infection , cervix , sex organ , vulva , epidemiology , gynecology , cross sectional study , population , anal canal , genotyping , obstetrics , cervical cancer , dermatology , genotype , surgery , biology , pathology , environmental health , rectum , cancer , biochemistry , gene , genetics
Background There are limited data on the epidemiology of HPV in different anatomical sites of female sex workers (FSW). We investigated the prevalence and concordance of cervical, vulval, oral and anal HPV among FSW in Ibadan, Nigeria. Methods FSWs aged 18–45 years were enrolled in a cross-sectional survey. After interview and clinical examination, samples were collected from mouth, cervix, vulva and anus. HPV genotyping was done with Anyplex II 28HPV assay. Multivariable analyses were performed to explore associated risk factors and concordance of HPV infections across sites. Results In total, 315 FSWs participated in the study with a mean age of 30–6.5 years. The prevalence of any HPV infection was 88% in the vulva, 84% in the cervix, 75% in the anus and 24% in the oral cavity. HPV 35 was the most prevalent and concordant high-risk type in the four sites. The risk factors for HPV infection by anatomic site varied. Conclusion This large study showed a high prevalence and concordance of HPV infections of cervical, vulval, oral and anal HPV among FSWs in Nigeria. The potential to acquire and transmit HPV is high in this population, and we highlighted the urgency to protect young women through HPV vaccination.