Open AccessGenomic analysis of Elsinoë arachidis reveals its potential pathogenic mechanism and the biosynthesis pathway of elsinochrome toxin
Author(s) -
Wenli Jiao,
Mengxue Xu,
Rujun Zhou,
Yiwei Fu,
Zibo Li,
Xue Cai-yun
Publication year - 2021
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0261487
Subject(s) - biology , genome , genetics , gene
Elsinochromes (ESCs) are virulence factors produced by Elsinoë arachidis which is the cause of peanut scab. However, the biosynthesis pathway of ESCs in E . arachidis has not been elucidated and the potential pathogenic mechanism of E . arachidis is poorly understood. In this study, we report a high-quality genome sequence of E . arachidis . The size of the E . arachidis genome is 33.18Mb, which is comparable to the Ascomycota genome (average 36.91 Mb), encoding 9174 predicted genes. The self-detoxification family including transporters and cytochrome P450 enzymes were analysis, candidate effectors and cell wall degrading enzymes were investigated as the pathogenicity genes by using PHI and CAZy databases. Additionally, the E . arachidis genome contains 24 secondary metabolism gene clusters, in which ESCB1 was identified as the core gene of ESC biosynthesis. Taken together, the genome sequence of E . arachidis provides a new route to explore its potential pathogenic mechanism and the biosynthesis pathway of ESCs.