Open AccessApplying historical data in a nonlinear mixed-effects model can reduce the number of control rats required for calculation of the relative potency of insulin analogues
Author(s) -
Emilie Prang Nielsen,
Søren Andersen,
Christian Brand,
Susanne Ditlevsen
Publication year - 2022
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0257750
Subject(s) - potency , bayesian probability , mixed model , computer science , insulin , control (management) , statistics , medicine , econometrics , mathematics , chemistry , artificial intelligence , biochemistry , in vitro