Open AccessPrevalence of latent tuberculosis infection among health workers in Afghanistan: A cross-sectional study
Author(s) -
Ghulam Qader Qader,
Mohammad Khaled Seddiq,
Khakerah Mohammad Rashidi,
Lutfullah Manzoor,
Azizullah Hamim,
Mir Habibullah Akhgar,
Laiqullrahman Rahman,
Sean Dryer,
Mariah Boyd-Boffa,
Aleefia Somji,
Muluken Melese,
Pedro Guillermo Suárez
Publication year - 2021
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0252307
Subject(s) - medicine , tuberculin , environmental health , latent tuberculosis , underweight , cross sectional study , body mass index , tuberculosis , health care , population , multivariate analysis , overweight , mycobacterium tuberculosis , pathology , economics , economic growth
Background About 26% of the world’s population may have latent tuberculosis infection (LTBI). Health care workers are a high-risk category because of their professional exposure. Methods This cross-sectional study assessed the LTBI burden among health care workers in Afghanistan, a high-TB-burden country. We selected health facilities using a systematic sampling technique and invited all workers at the targeted health facilities to participate. Participants were interviewed about sociodemographic and exposure variables and received tuberculin skin tests for LTBI. Results Of the 4,648 health care workers invited to participate, 3,686 had tuberculin skin tests. The prevalence of LTBI was found to be 47.2% (1,738 workers). Multivariate analysis showed that a body mass index of ≥ 30 and marriage were associated with an increased risk of LTBI. Underweight (body mass index of ≤ 18 and below) and normal body mass index had no association with increased risk of LTBI. Conclusion LTBI is high among health care workers in Afghanistan. We recommend instituting infection control measures in health facilities and screening workers for timely TB diagnosis.