Open AccessSpatial heterogeneity of cutaneous blood flow respiratory-related oscillations quantified via laser speckle contrast imaging
Author(s) -
Irina Mizeva,
Elena Potapova,
Viktor Dremin,
Igor Kozlov,
Andrey V. Dunaev
Publication year - 2021
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0252296
Subject(s) - context (archaeology) , speckle pattern , blood flow , oscillation (cell signaling) , circulatory system , coherence (philosophical gambling strategy) , breathing , synchronization (alternating current) , respiration , spatial frequency , respiratory system , neuroscience , computer science , biomedical engineering , cardiology , medicine , physics , optics , anesthesia , anatomy , biology , telecommunications , paleontology , channel (broadcasting) , genetics , quantum mechanics
LSCI technique provides experimental data which can be considered in the context of spatial blood flow coherency. Analysis of vascular tone oscillations gives additional information to ensure a better understanding of the mechanisms affecting microvascular physiology. The oscillations with different frequencies are due to different physiological mechanisms. The reasons for the generation of peripheral blood flow oscillations in the 0.14–0.6 Hz frequency band are as follows: cardio-respiratory interactions, pressure variations in the venous part of the circulatory system, and the effect of the sympathetic nervous system on the vascular tone. Earlier, we described the spatial heterogeneity of around 0.3 Hz oscillations and this motivated us to continue the research to find the conditions for the occurrence of spatial phase synchronization. For this purpose, a number of physiological tests (controlled respiration, breath holder, and venous occlusion tests) which influence the blood flow oscillations of 0.14–0.6 Hz were considered, an appropriate measurement system and the required data processing algorithms were developed. At spontaneous respiration, the oscillations with frequencies around 0.3 Hz were stochastic, whereas all the performed tests induced an increase in spatial coherence. The protocols and methods proposed here can help to clarify whether the heterogeneity of respiratory-related blood flow oscillations exists on the skin surface.