Open AccessReducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial
Author(s) -
Mark Kaddumukasa,
Josephine Nambi Najjuma,
Scovia Nalugo Mbalinda,
Martin N. Kaddumukasa,
Jane Nakibuuka,
Christopher J. Burant,
Shirley M. Moore,
Carol Blixen,
Elly Katabira,
Martha Sajatovic
Publication year - 2021
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0251662
Subject(s) - randomized controlled trial , medicine , stroke (engine) , intervention (counseling) , physical therapy , nursing , mechanical engineering , engineering
Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planned randomized controlled trial builds on promising preliminary data. Methods A total of 246 Ugandan adults will be recruited randomized to experimental intervention vs. enhanced treatment control. Intervention participants will receive six weekly group-format stroke risk reduction self-management training sessions, and the controls will receive information on cardiovascular risk. The primary study outcome is systolic B.P. measured at baseline, 13-week, 24 weeks (6 months). Secondary outcomes include other biological and behavioral stroke risk factors. Discussion The curriculum-guided self-management TargetEd MAnageMent Intervention (TEAM) program is anticipated to reduce the stroke burden in Uganda. Trial registration ClinicalTrials.gov identifier: NCT04685408 , registered on 28 December 2020.