Open AccessPreliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency
Author(s) -
Bożena Muszyńska,
Ewelina Szacawa,
Dorota BederskaŁojewska,
Katarzyna Dudek,
Bartosz Pomierny,
Anna Włodarczyk,
Katarzyna Kała,
Jan Lazur,
Piotr Suchocki,
Bogusława Budziszewska,
D. Bednarek,
M. Pieszka
Publication year - 2020
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0233456
Subject(s) - lentinula , selenium , mycelium , mushroom , selenium deficiency , zoology , food science , ruminant , biology , lentinus , edible mushroom , body weight , chemistry , botany , biochemistry , glutathione peroxidase , agronomy , endocrinology , antioxidant , catalase , organic chemistry , crop
The presence of selenium in European soil is low and this causes its deficiency in livestock and, in consequence, in humans. This study aimed to obtain Lentinula ( L .) edodes mycelium with the maximum content of selenium. This species was used for experiment based on its documented medicinal properties. Calves were fed with selenium-enriched L . edode s mycelium, and serum selenium concentration, average daily weight gains and selected immune parameters were estimated. The selenium-enriched mushroom was found to be safe based on cytotoxicity tests (MTT and LDH tests) and for this reason it was used for further experiments. The mean quantity of selenium in the serum of calves fed with selenium-enriched L . edodes mycelium was significantly higher than that of control calves. Additionally, the calves fed with selenium-enriched L . edodes mycelium had higher body weight gains than those of control calves. White blood cell counts and subpopulations of lymphocytes in the experimental and control calves were within the reference range. The administration of L . edodes enriched with selenium had a beneficial effect on state of health of the calves.