Open AccessLong range correlations of the ion current in SV channels. Met3PbCl influence study
Author(s) -
Janusz Miśkiewicz,
Ze Trela,
Zbigniew Burdach,
W. Karcz,
Wanda Balińska-Miśkiewicz
Publication year - 2020
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0229433
Subject(s) - detrended fluctuation analysis , current (fluid) , range (aeronautics) , hurst exponent , series (stratigraphy) , dwell time , ion channel , ion , statistical physics , statistics , physics , analytical chemistry (journal) , chemistry , mathematics , materials science , thermodynamics , biology , medicine , chromatography , scaling , paleontology , clinical psychology , geometry , quantum mechanics , composite material , biochemistry , receptor
The long-range correlations within the current signal time series of the Beta vulgaris vacuolar membrane under the influence of organolead compound (Met 3 PbCl) are investigated. The current time series is transformed into a dwell time series. Then the rescaled range and detrended fluctuations analyses are used. It is shown that the presence of Met 3 PbCl in the solution decreases the mean value of the Hurst exponent and therefore influences the long-range correlations in ionic channel current. This observation is statistically significant. An ion channel model is built and the experimental results reconstructed and analysed.