Open AccessObstructive sleep apnea and hypopnea syndrome in patients admitted in a tertiary hospital in Cameroon: Prevalence and associated factors
Author(s) -
V. Poka-Mayap,
D. Balkissou Adamou,
M. Massongo,
Steve Voufouo Sonwa,
Jacqueline Alime,
Ben Patrick Michel Moutlen,
Alfred K. Njamnshi,
André Noseda,
E.W. Pefura-Yone
Publication year - 2020
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0227778
Subject(s) - medicine , obstructive sleep apnea , hypopnea , body mass index , epworth sleepiness scale , odds ratio , tertiary referral hospital , pediatrics , polysomnography , sleep apnea , cross sectional study , logistic regression , apnea , physical therapy , retrospective cohort study , pathology
Purpose Obstructive sleep apnea and hypopnea syndrome (OSAHS) is poorly documented in Sub-Saharan Africa, especially in the hospital setting. The aim of this study was to determine its prevalence and to investigate the associated factors in patients admitted in a tertiary referral hospital in Cameroon. Methods In this cross-sectional study conducted in the Cardiology, Endocrinology and Neurology departments of the Yaounde Central Hospital; all patients aged 21 and older were included consecutively. A sample of randomly selected patients was recorded using a portable sleep monitoring device (PMD). OSAHS was defined as apnea-hypopnea index (AHI) ≥ 5/hour (with > 50% of events being obstructive) and moderate to severe OSAHS as an AHI > 15/hour. Logistic regression was used to identify factors associated to OSAHS. Results Of the 359 patients included, 202 (56.3%) patients were women. The mean age (standard deviation) was 58 (16) years. The prevalence of OSAHS assessed by PMD (95% CI) was 57.7% (48.5–66.9%), 53.8% in men and 62.7% in women (p = 0.44). The median (25 th -75 th percentiles) AHI, body mass index and Epworth Sleepiness Scale score of OSAHS patients were 17 (10.6–26.9)/hour, 27.4 (24.7–31.6) kg/m 2 and 7 (5–9) respectively. The only factor associated to moderate to severe OSAHS was hypertension [odds ratio (95% CI)]: 3.24 (1.08–9.72), p = 0.036. Conclusion OSAHS is a common condition in patients in this health care centre of Cameroon. In the hospital setting, screening for OSAHS in patients with hypertension is recommended.