Open AccessElevated renal tissue oxygenation in premature fetal growth restricted neonates: An observational study
Author(s) -
Fieke Terstappen,
Nina D. Paauw,
Thomas Alderliesten,
Jaap A. Joles,
Daniel C. Vijlbrief,
A. Titia Lely,
Petra Lemmers
Publication year - 2018
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0204268
Subject(s) - medicine , cardiology , fetus , kidney , gestation , renal blood flow , pregnancy , biology , genetics
Background Fetal growth restriction (FGR) is associated with an increased risk for kidney disease in later life. Studies reporting on early signs of renal disturbances in FGR are sparse and mostly include invasive measurements, which limit the possibility for early identification and prevention. We aim to investigate whether renal tissue oxygen saturation (rSO 2 ) measured with near-infrared spectroscopy (NIRS) and the derived value fractional tissue oxygen extraction (FTOE) differ between premature FGR and control neonates in the first three days after birth. Methods Nine FGR and seven control neonates born <32 weeks of gestation were included. FGR was defined as biometry