Open AccessDetection of cooperatively bound transcription factor pairs using ChIP-seq peak intensities and expectation maximization
Author(s) -
Vishaka Gopalan,
Rahul Siddharthan,
Sandeep Krishna
Publication year - 2018
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0199771
Subject(s) - enhancer , transcription factor , computational biology , expectation–maximization algorithm , binding site , cooperative binding , computer science , promoter , dna binding site , dna , dna sequencing , sequence (biology) , maximization , gene , biology , algorithm , genetics , gene expression , maximum likelihood , mathematics , statistics , mathematical optimization