Open AccessThe transverse four-chamber view for the assessment of atrial tissue deformation in the fetus
Author(s) -
J. Steinhard,
Andreas Entenmann,
E. Valk,
Ralf Schmitz,
J. Heinig,
Kai Thorsten Laser,
Miriam Michel
Publication year - 2018
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0199581
Subject(s) - transverse plane , medicine , fetus , cardiology , strain (injury) , transverse diameter , anatomy , nuclear medicine , pregnancy , biology , genetics
Aims To determine if atrial tissue deformation (peak strain, PS) and time to peak strain (TTPS) can be assessed in the fetus, with identification of best echocardiographic plane. Materials and methods Pulsed-wave tissue Doppler study of a longitudinal and a transverse four-chamber view (FCV) in each of 20 healthy fetuses. Determination of PS and TTPS in regions of interest (ROI), viz ., lateral walls of the right and left atria (RA, LA); comparison of values depending on section plane, with results-based discussion of the physiology of fetal atrial deformation and of possible clinical uses. Results PS and TTPS could be determined on transverse FCV in 91% of subjects and in 61% on longitudinal FCV. Transverse PS and TTPS were significantly higher than longitudinal (p = 0.0001). Transverse PS was significantly higher in RA than in LA (26.9% vs . 17.3%, p = 0.034), and transverse TTPS was significantly shorter in RA than in LA (p = 0.034). Conclusion Atrial radial PS and TTPS determinations are possible in the fetus. The transverse FCV is best suited for these. The highest PS values and shortest TTPS values are found in ROI representing the RA. Our findings may contribute to detailed intrauterine assessment of atrial and ventricular myocardial function.