Open AccessPopulation-based study of chlamydial and gonococcal infections among women in Shenzhen, China: Implications for programme planning
Author(s) -
Zhenzhou Luo,
Wu Li,
Qiuhong Wu,
Li Zhang,
Lu Tian,
Lanlan Liu,
Yi Ding,
Jing Yuan,
Zhongwei Chen,
Liping Lan,
Xiaobing Wu,
Yumao Cai,
Fu-Chang Hong,
Tiejian Feng,
Min Zhang,
XiangSheng Chen
Publication year - 2018
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0196516
Subject(s) - medicine , odds ratio , confidence interval , chlamydia , chlamydia trachomatis , obstetrics , population , condom , pregnancy , demography , gonorrhea , gynecology , environmental health , immunology , syphilis , biology , human immunodeficiency virus (hiv) , sociology , genetics
This study was aimed to estimate the prevalences of chlamydia (CT) and gonococcal (NG) infections and explore risk factors associated with the CT infection among women in Shenzhen, China. We collected socio-demographic and clinical data from women (aged 20–60) and determined positivity of CT or NG by nucleic acid amplification test (NAAT) with self-collected urine specimens. We estimated prevalence of CT and NG and determined risk factors associated with CT infection. Among 9,207 participants, 4.12% (95% confidence interval [CI], 3.71%-4.53%) tested positive for CT and 0.17% (95% CIs, 0.09%-0.25%) for NG. Factors significantly associated with CT infection included being an ethnic minority (ethnicity other than Han China) (Adjusted odds ratio [AOR], 1.9; 95% CI, 1.2–3.0), using methods other than condom for contraception (AOR, 1.5; 95% CI, 1.2–1.8), having a history of adverse pregnancy outcomes (AOR, 1.4; 95% CI, 1.1–1.8), and experiencing reproductive tract symptoms in the past three months (AOR, 1.3; 95% CI, 1.0–1.7). we found that CT infection is prevalent among women in Shenzhen, China and associated with both demographic and behavioral factors. A comprehensive CT screening, surveillance and treatment programme targeting this population is warranted.