Open AccessGraphical and statistical analyses of the oculocardiac reflex during a non-invasive intracranial pressure measurement
Author(s) -
Yasin Hamarat,
Laimonas Bartušis,
Mantas Deimantavičius,
Lina Šiaudvytytė,
Ingrida Janulevičienė,
Arminas Ragauskas,
Eric M. Bershad,
Javier Fandiño,
Jenny Kienzler,
Elke Remonda,
Vaidas Matijošaitis,
Daiva Rastenytė,
Kęstutis Petrikonis,
Kristina Berškienė,
Rolandas Žakelis
Publication year - 2018
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0196155
Subject(s) - oculocardiac reflex , medicine , heart rate , incidence (geometry) , reflex , anesthesia , blood pressure , physics , optics
Purpose This study aimed to examine the incidence of the oculocardiac reflex during a non-invasive intracranial pressure measurement when gradual external pressure was applied to the orbital tissues and eye. Methods Patients (n = 101) and healthy volunteers (n = 56) aged 20–75 years who underwent a non-invasive intracranial pressure measurement were included in this retrospective oculocardiac reflex analysis. Prespecified thresholds greater than a 10% or 20% decrease in the heart rate from baseline were used to determine the incidence of the oculocardiac reflex. Results None of the subjects had a greater than 20% decrease in heart rate from baseline. Four subjects had a greater than 10% decrease in heart rate from baseline, representing 0.9% of the total pressure steps. Three of these subjects were healthy volunteers, and one was a glaucoma patient. Conclusion The incidence of the oculocardiac reflex during a non-invasive intracranial pressure measurement procedure was very low and not associated with any clinically relevant effects.