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Identifying artemisinin resistance from parasite clearance half-life data with a simple Shiny web application
Author(s) -
Sai Thein Than Tun,
Yoel Lubell,
Arjen M. Dondorp,
Tom Fieldman,
Kyaw Myo Tun,
O. Celhay,
Xin Hui S Chan,
Sompob Saralamba,
Lisa J. White
Publication year - 2017
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0177840
Subject(s) - artemisinin , malaria , plasmodium falciparum , drug resistance , biology , medicine , immunology , microbiology and biotechnology
The emergence of artemisinin-resistant Plasmodium falciparum malaria is a major threat to malaria elimination. New tools for supporting the surveillance of artemisinin resistance are critical for current and future malaria control and elimination strategies. We have developed an open-access, user-friendly, web-based tool to analyse parasite clearance half-life data of P . falciparum infected patients after treatment with artemisinin derivatives, so that resistance to artemisinin can be identified. The tool can be accessed at bit.ly/id_artemisinin_resistance .

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