Open AccessCorrection: Regulation of α-Transducin and α-Gustducin Expression by a High Protein Diet in the Pig Gastrointestinal Tract
Author(s) -
Roberto De Giorgio,
Maurizio Mazzoni,
Claudia Vallorani,
Rocco Latorre,
Cristiano Bombardi,
Maria Laura Bacci,
Monica Forni,
Mirella Falconi,
Catia Sternini,
Paolo Clavenzani
Publication year - 2016
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0152647
Subject(s) - gastrointestinal tract , transducin , biology , microbiology and biotechnology , biochemistry , g protein , signal transduction
The expression of taste receptors (TASRs) and their signalling molecules in the gastrointestinal\ud(GI) epithelial cells, including enteroendocrine cells (EECs), suggests they participate\udin chemosensing mechanisms influencing GI physiology via the release of endocrine messengers.\udTASRs mediate gustatory signalling by interacting with different transducers,\udincluding α-gustducin (Gαgust) and α-transducin (Gαtran) G protein subunits. This study\udtested whether Gαtran and Gαgust immunoreactive (-IR) cells are affected by a short-term\ud(3 days) and long-term (30 days) high protein (Hp) diet in the pig GI tract