Open AccessRiyadh Mother and Baby Multicenter Cohort Study: The Cohort Profile
Author(s) -
Hayfaa Wahabi,
Amel Fayed,
Samia Esmaeil,
Rasmieh Alzeidan,
Mamoun Elawad,
Rabeena Tabassum,
Shehnaz Hansoti,
Mohie Edein Magzoup,
Hanan M. Al-Kadri,
Elham Elsherif,
Hazim Al-Mandil,
Ghadeer AlShaikh,
Nasria Zakaria
Publication year - 2016
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0150297
Subject(s) - medicine , gestational diabetes , obstetrics , cohort , overweight , pregnancy , gestational hypertension , cohort study , preeclampsia , caesarean section , obesity , birth weight , pediatrics , diabetes mellitus , gestational age , small for gestational age , gestation , endocrinology , genetics , biology
Objectives To assess the effects of non-communicable diseases, such as diabetes, hypertension and obesity, on the mother and the infant. Methods A multicentre cohort study was conducted in three hospitals in the city of Riyadh in Saudi Arabia. All Saudi women and their babies who delivered in participating hospitals were eligible for recruitment. Data on socio-demographic characteristics in addition to the maternal and neonatal outcomes of pregnancy were collected. The cohort demographic profile was recorded and the prevalence of maternal conditions including gestational diabetes, pre-gestational diabetes, hypertensive disorders in pregnancy and obesity were estimated. Findings The total number of women who delivered in participating hospitals during the study period was 16,012 of which 14,568 women participated in the study. The mean age of the participants was 29 ± 5.9 years and over 40% were university graduates. Most of the participants were housewives, 70% were high or middle income and 22% were exposed to secondhand smoke. Of the total cohort, 24% were married to a first cousin. More than 68% of the participants were either overweight or obese. The preterm delivery rate was 9%, while 1.5% of the deliveries were postdate. The stillbirth rate was 13/1000 live birth. The prevalence of gestational diabetes was 24% and that of pre-gestational diabetes was 4.3%. The preeclampsia prevalence was 1.1%. The labour induction rate was 15.5% and the cesarean section rate was 25%. Conclusion Pregnant women in Saudi Arabia have a unique demographic profile. The prevalence of obesity and diabetes in pregnancy are among the highest in the world.