Open AccessAssociation of Habitual Patterns and Types of Physical Activity and Inactivity with MRI-Determined Total Volumes of Visceral and Subcutaneous Abdominal Adipose Tissue in a General White Population
Author(s) -
Karina Fischer,
Daniela Rüttgers,
HansPeter Müller,
Gunnar Jacobs,
Jan Kassubek,
Wolfgang Lieb,
Ute Nöthlings
Publication year - 2015
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0143925
Subject(s) - medicine , adipose tissue , population , intra abdominal fat , metabolic equivalent , exploratory analysis , cross sectional study , logistic regression , demography , endocrinology , physical activity , visceral fat , obesity , physical therapy , pathology , insulin resistance , data science , environmental health , sociology , computer science
Population-based evidence for the role of habitual physical activity (PA) in the accumulation of visceral (VAT) and subcutaneous (SAAT) abdominal adipose tissue is limited. We investigated if usual patterns and types of self-reported PA and inactivity were associated with VAT and SAAT in a general white population. Total volumes of VAT and SAAT were quantified by magnetic resonance imaging in 583 men and women (61 ± 11.9 y; BMI 27.2 ± 4.4 kg/m 2 ). Past-year PA and inactivity were self-reported by questionnaire. Exploratory activity patterns (APAT) were derived by principal components analysis. Cross-sectional associations between individual activities, total PA in terms of metabolic equivalents (PA MET), or overall APAT and either VAT or SAAT were analyzed by multivariable-adjusted robust or generalized linear regression models. Whereas vigorous-intensity PA (VPA) was negatively associated with both VAT and SAAT, associations between total PA MET, moderate-intensity PA (MPA), or inactivity and VAT and/or SAAT depended on sex. There was also evidence of a threshold effect in some of these relationships. Total PA MET was more strongly associated with VAT in men ( B = -3.3 ± 1.4; P = 0.02) than women ( B = -2.1 ± 1.1; P = 0.07), but was more strongly associated with SAAT in women ( B = -5.7 ± 2.5; P = 0.05) than men ( B = -1.7 ± 1.6; P = 0.3). Men (-1.52 dm 3 or -1.89 dm 3 ) and women (-1.15 dm 3 or -2.61 dm 3 ) in the highest (>6.8 h/wk VPA) or second (4.0–6.8 h/wk VPA) tertile of an APAT rich in VPA, had lower VAT and SAAT, respectively, than those in the lowest (<4.0 h/wk VPA) tertile ( P ≤ 0.016; P trend ≤ 0.0005). They also had lower VAT and SAAT than those with APAT rich in MPA and/or inactivity only. In conclusion, our results suggest that in white populations, habitual APAT rich in MPA might be insufficient to impact on accumulation of VAT or SAAT. APAT including ≥4.0–6.8 h/wk VPA, by contrast, are more strongly associated with lower VAT and SAAT.