Open AccessStructure Based Thermostability Prediction Models for Protein Single Point Mutations with Machine Learning Tools
Author(s) -
Lei Jia,
Ramya Yarlagadda,
Charles C. Reed
Publication year - 2015
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0138022
Subject(s) - thermostability , support vector machine , computer science , artificial intelligence , protein structure prediction , machine learning , protein folding , overfitting , protein engineering , ensemble learning , lasso (programming language) , in silico , computational biology , data mining , protein structure , biology , artificial neural network , genetics , biochemistry , world wide web , enzyme , gene