Open AccessObsessive Compulsive Personality Disorder and Parkinson’s Disease
Author(s) -
Alessandra Nicoletti,
Antonina Luca,
Loredana Raciti,
Donatella Contrafatto,
Elisa Bruno,
Valeria Dibilio,
Giorgia Sciacca,
Giovanni Mostile,
Antonio Petralia,
Mario Zappia
Publication year - 2013
Publication title -
plos one
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.99
H-Index - 332
ISSN - 1932-6203
DOI - 10.1371/journal.pone.0054822
Subject(s) - parkinson's disease , personality , disease , clinical psychology , psychiatry , medicine , obsessive compulsive , psychology , social psychology
Objectives To evaluate the frequency of personality disorders in Parkinson’s disease (PD) patients and in a group of healthy controls. Methods Patients affected by PD diagnosed according to the United Kingdom Parkinson’s disease Society Brain Bank diagnostic criteria and a group of healthy controls were enrolled in the study. PD patients with cognitive impairment were excluded from the study. Structured Clinical Interview for Personality Disorders-II (SCID-II) has been performed to evaluate the presence of personality disorders. Presence of personality disorders, diagnosed according to the DSM-IV, was confirmed by a psychiatric interview. Clinical and pharmacological data were also recorded using a standardized questionnaire. Results 100 PD patients (57 men; mean age 59.0±10.2 years) and 100 healthy subjects (52 men; mean age 58.1±11.4 years) were enrolled in the study. The most common personality disorder was the obsessive-compulsive personality disorder diagnosed in 40 PD patients and in 10 controls subjects ( p-value <0.0001) followed by the depressive personality disorder recorded in 14 PD patients and 4 control subjects ( p-value 0.02). Obsessive-compulsive personality disorder was also found in 8 out of 16 de novo PD patients with a short disease duration. Conclusion PD patients presented a high frequency of obsessive-compulsive personality disorder that does not seem to be related with both disease duration and dopaminergic therapy.