Open AccessFXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice
Author(s) -
Beibei Zhang,
Jing Li,
Xianlong Zong,
Jianling Wang,
Lianlian Xin,
Haiyao Song,
Wenxue Zhang,
Stephane Koda,
Hui Hua,
Bo Zhang,
Qian Yu,
Kuiyang Zheng,
Chao Yan
Publication year - 2022
Publication title -
plos neglected tropical diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.99
H-Index - 135
eISSN - 1935-2735
pISSN - 1935-2727
DOI - 10.1371/journal.pntd.0010651
Subject(s) - schistosoma japonicum , autophagy , homeostasis , liver injury , flatworm , bile acid , biology , schistosomiasis , schistosoma , cholestasis , microbiology and biotechnology , immunology , schistosoma mansoni , helminths , endocrinology , biochemistry , ecology , apoptosis