Open AccessFXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice
Author(s) -
Beibei Zhang,
Jing Li,
Xianlong Zong,
Jianling Wang,
Lianlian Xin,
Haiyao Song,
Wenxue Zhang,
Stephane Koda,
Hui Hua,
Bo Zhang,
Qian Yu,
Kuiyang Zheng,
Chao Yan
Publication year - 2022
Publication title -
plos neglected tropical diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.99
H-Index - 135
eISSN - 1935-2735
pISSN - 1935-2727
DOI - 10.1371/journal.pntd.0010651
Subject(s) - farnesoid x receptor , medicine , bile acid , liver injury , endocrinology , biology , autophagy , schistosoma japonicum , homeostasis , hepatocyte , western blot , nuclear receptor , immunology , transcription factor , schistosomiasis , biochemistry , apoptosis , helminths , in vitro , gene
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