Open AccessCOX-2 is required to mediate crosstalk of ROS-dependent activation of MAPK/NF-κB signaling with pro-inflammatory response and defense-related NO enhancement during challenge of macrophage-like cell line with Giardia duodenalis
Author(s) -
Yudan Zhao,
Yongwu Yang,
Min Liu,
Xuening Qin,
Xiran Yu,
Huimin Zhao,
Xiaoyun Li,
Wei Li
Publication year - 2022
Publication title -
plos neglected tropical diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.99
H-Index - 135
eISSN - 1935-2735
pISSN - 1935-2727
DOI - 10.1371/journal.pntd.0010402
Subject(s) - crosstalk , microbiology and biotechnology , mapk/erk pathway , macrophage , nf κb , nfkb1 , signal transduction , inflammation , cancer research , immunology , chemistry , biology , transcription factor , physics , genetics , in vitro , gene , optics
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