Open AccessDiagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement
Author(s) -
Ilse C. E. Hendriksen,
Juliet MwangaAmumpaire,
Lorenz von Seidlein,
George Mtove,
Lisa J. White,
Rasaq Olaosebikan,
Sue J. Lee,
Antoinette Tshefu,
Charles J. Woodrow,
Ben Amos,
Corine Karema,
Somporn Saiwaew,
Kathryn Maitland,
Ermelinda Gomes,
Wirichada Pan-ngum,
Samwel Gesase,
Kamolrat Silamut,
Hugh Reyburn,
Sarah Joseph,
Kesinee Chotivanich,
Caterina Fanello,
Nicholas Day,
Nicholas J. White,
Arjen M. Dondorp
Publication year - 2012
Publication title -
plos medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.847
H-Index - 228
eISSN - 1549-1676
pISSN - 1549-1277
DOI - 10.1371/journal.pmed.1001297
Subject(s) - malaria , artesunate , medicine , plasmodium falciparum , quinine , parasitemia , odds ratio , prospective cohort study , severe malaria , immunology , pediatrics
Arjen Dondorp and colleagues investigate whether the plasma level of Plasmodium falciparum histidine-rich protein 2 can be used to distinguish between severe malaria and other severe febrile illness in African children with malaria.