Open AccessIntragenomic variation in non-adaptive nucleotide biases causes underestimation of selection on synonymous codon usage
Author(s) -
Alexander L Cope,
Premal Shah
Publication year - 2022
Publication title -
plos genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.587
H-Index - 233
eISSN - 1553-7404
pISSN - 1553-7390
DOI - 10.1371/journal.pgen.1010256
Subject(s) - biology , codon usage bias , natural selection , genetics , genome , adaptive evolution , synonymous substitution , selection (genetic algorithm) , evolutionary biology , negative selection , gene , genetic variation , silent mutation , adaptation (eye) , mutation , computational biology , machine learning , computer science , missense mutation , neuroscience