Open AccessAn in vivo drug repurposing screen and transcriptional analyses reveals the serotonin pathway and GSK3 as major therapeutic targets for NGLY1 deficiency
Author(s) -
Kevin A. Hope,
Alexys R. Berman,
Randall T. Peterson,
Clement Y. Chow
Publication year - 2022
Publication title -
plos genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.587
H-Index - 233
eISSN - 1553-7404
pISSN - 1553-7390
DOI - 10.1371/journal.pgen.1010228
Subject(s) - biology , gsk 3 , drug repositioning , mdma , gene knockdown , pharmacology , microbiology and biotechnology , genetics , signal transduction , drug , gene
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