Open AccessIntegrated analysis of direct and proxy genome wide association studies highlights polygenicity of Alzheimer’s disease outside of the APOE region
Author(s) -
Javier de la Fuente,
Andrew D. Grotzinger,
Riccardo E. Marioni,
Michel G. Nivard,
Elliot M. TuckerDrob
Publication year - 2022
Publication title -
plos genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.587
H-Index - 233
eISSN - 1553-7404
pISSN - 1553-7390
DOI - 10.1371/journal.pgen.1010208
Subject(s) - genome wide association study , heritability , biology , genetic association , biobank , genetic architecture , snp , genetics , genomics , imputation (statistics) , apolipoprotein e , missing heritability problem , computational biology , single nucleotide polymorphism , disease , quantitative trait locus , genome , medicine , computer science , gene , missing data , genotype , machine learning
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