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Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)
Author(s) -
Gabriel Foley,
Ariane Mora,
Connie M. Ross,
Scott Bottoms,
Leander Sützl,
Marnie L. Lamprecht,
Julian Zaugg,
Alexandra Essebier,
Brad Balderson,
R.B. Newell,
Raine E. S. Thomson,
Boštjan Kobe,
Ross Barnard,
Luke W. Guddat,
Gerhard Schenk,
Jörg Carsten,
Yosephine Gumulya,
Burkhard Rost,
Dietmar Haltrich,
Volker Sieber,
Elizabeth M. J. Gillam,
Mikael Bodén
Publication year - 2022
Publication title -
plos computational biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.628
H-Index - 182
eISSN - 1553-7358
pISSN - 1553-734X
DOI - 10.1371/journal.pcbi.1010633
Subject(s) - grasp , indel , sequence (biology) , computational biology , protein engineering , biology , representation (politics) , sequence alignment , inference , multiple sequence alignment , protein sequencing , most recent common ancestor , computer science , genetics , gene , phylogenetics , artificial intelligence , peptide sequence , enzyme , biochemistry , programming language , politics , genotype , single nucleotide polymorphism , political science , law

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