Open AccessPrimary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function
Author(s) -
Neal K. Bennett,
Hiroki J. Nakaoka,
Danny Laurent,
Ross A. Okimoto,
Yoshitaka J. Sei,
Andrew E. Horvai,
Trever G. Bivona,
Johanna ten Hoeve,
Thomas G. Graeber,
Ken Nakamura,
Jean L. Nakamura
Publication year - 2022
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.3001753
Subject(s) - biology , gene knockdown , respiratory chain , warburg effect , cancer research , anaerobic glycolysis , in vivo , mitochondrial respiratory chain , glycolysis , mitochondrion , primary tumor , cancer , cancer cell , microbiology and biotechnology , cell culture , metastasis , genetics , biochemistry , metabolism