Open AccessStructure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface
Author(s) -
Yunseok Heo,
Naito Ishimoto,
Ye-Eun Jeon,
Ji-Hye Yun,
Mio Ohki,
Yuki Anraku,
Mariko Sasaki,
Sotaro Kita,
Hideo Fukuhara,
Tatsuya Ikuta,
Kouki Kawakami,
Asuka Inoue,
Katsumi Maenaka,
J.R.H. Tame,
Weontae Lee,
Sam-Yong Park
Publication year - 2022
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.3001714
Subject(s) - galanin , biology , galanin receptor , g protein coupled receptor , neuropeptide , heterotrimeric g protein , receptor , ligand (biochemistry) , g protein , microbiology and biotechnology , neuroscience , biochemistry