A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models | Zendy

Dharaminder Singh | Zendy; Sudhir P. Deosarkar | Zendy; Elaine Cadogan | Zendy; Vikki Flemington | Zendy; Alysha Bray | Zendy; Jingwen Zhang | Zendy; Ronald S. Reiserer | Zendy; David K. Schaffer | Zendy; Gregory B. Gerken | Zendy; Clayton M. Britt | Zendy; Erik M. Werner | Zendy; Francis D. Gibbons | Zendy; Tomasz Kostrzewski | Zendy; Christopher E. Chambers | Zendy; Emma Jane Davies | Zendy; Antonio Ramos Montoya | Zendy; Jacqueline H. L. Fok | Zendy; David Hughes | Zendy; Kristin Fabre | Zendy; Matthew P. Wagoner | Zendy; John P. Wikswo | Zendy; Clay W. Scott | Zendy

Open Access

A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models

Author(s) -

Dharaminder Singh,

Sudhir P. Deosarkar,

Elaine Cadogan,

Vikki Flemington,

Alysha Bray,

Jingwen Zhang,

Ronald S. Reiserer,

David K. Schaffer,

Gregory B. Gerken,

Clayton M. Britt,

Erik M. Werner,

Francis D. Gibbons,

Tomasz Kostrzewski,

Christopher E. Chambers,

Emma Jane Davies,

Antonio Ramos Montoya,

Jacqueline H. L. Fok,

David Hughes,

Kristin Fabre,

Matthew P. Wagoner,

John P. Wikswo,

Clay W. Scott

Publication year - 2022

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.3001624

Subject(s) - in vivo , biology , pharmacokinetics , in vitro , pharmacology , cell culture , in vitro toxicology , biochemistry , microbiology and biotechnology , genetics

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