PiVR: An affordable and versatile closed-loop platform to study unrestrained sensorimotor behavior | Zendy

David Tadres | Zendy; Matthieu Louis | Zendy

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PiVR: An affordable and versatile closed-loop platform to study unrestrained sensorimotor behavior

Author(s) -

David Tadres,

Matthieu Louis

Publication year - 2020

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.3000712

Subject(s) - phototaxis , optogenetics , biology , chemotaxis , neuroscience , sensory system , drosophila (subgenus) , chemotaxis assay , zebrafish , biochemistry , botany , receptor , gene

Tools enabling closed-loop experiments are crucial to delineate causal relationships between the activity of genetically labeled neurons and specific behaviors. We developed the Raspberry Pi Virtual Reality (PiVR) system to conduct closed-loop optogenetic stimulation of neural functions in unrestrained animals. PiVR is an experimental platform that operates at high temporal resolution (70 Hz) with low latencies (<30 milliseconds), while being affordable (

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