Open AccessBrain Endothelial Cells Control Fertility through Ovarian-Steroid–Dependent Release of Semaphorin 3A
Author(s) -
Paolo Giacobini,
Jyoti Parkash,
Céline Campagne,
Andréa Messina,
Filippo Casoni,
Charlotte Vanacker,
Fanny Langlet,
Barbara Hobo,
Gabriella Cagi,
Sarah Gallet,
Naresh K. Hanchate,
Danièle Mazur,
Masahiko Taniguchi,
Massimiliano Mazzone,
Joost Verhaagen,
Philippe Ciofi,
Sébastien G. Bouret,
Luca Tamag,
Vincent Prévot
Publication year - 2014
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001808
Subject(s) - biology , semaphorin , neuropilin 1 , sema3a , gonadotropin releasing hormone , microbiology and biotechnology , endocrinology , medicine , vascular endothelial growth factor a , receptor , hormone , vascular endothelial growth factor , luteinizing hormone , cancer research , biochemistry , vegf receptors
Endothelial-cell–derived Sema3A promotes axonal outgrowth and plasticity and thereby regulates neurohormone release in the adult rodent brain in response to the ovarian cycle.