Open AccessLinking Inflammation to Natural Killer T Cell Activation
Author(s) -
Mariolina Salio,
Vincenzo Cerundolo
Publication year - 2009
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000226
Subject(s) - inflammation , biology , immune system , immunology , immunity , innate immune system , microbiology and biotechnology , natural killer cell , cytotoxic t cell , genetics , in vitro
Immune activation is often associated with inflammation, but inflammation's role in the expansion of antigen-specific immune responses remains unclear. This primer focuses on recent findings that show how specific natural killer T cells are activated by inflammatory messengers, thus illuminating the cellular and molecular links between immunity and inflammation.