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Epidemiological Review of Francisella Tularensis: A Case Study in the Complications of Dual Diagnoses
Author(s) -
Ralph A Stidham,
David B. Freeman,
Robert L. von Tersch,
Peter J. Sullivan,
Samantha Tostenson
Publication year - 2018
Publication title -
plos currents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.282
H-Index - 49
ISSN - 2157-3999
DOI - 10.1371/currents.outbreaks.8eb0b55f377abc2d250314bbb8fc9d6d
Subject(s) - francisella tularensis , tularemia , medicine , francisella , veterinary medicine , pathology , biology , virulence , biochemistry , gene
Tularemia is a rare but potentially fatal disease that develops in numerous wild and domestic animals, including lagomorphs, rodents, cats, and humans.  Francisella tularensis bacterium, the causative agent of tularemia, was identified by veterinary personnel at Fort Riley, Kansas during a routine post-mortum evaluation of a domestic feline. However, before formal diagnosis was confirmed, the sample was sent and prepared for rabies testing at the Department of Defense (DoD) U.S. Army Public Health Command Central (PHC-C), Food Analysis and Diagnostic Laboratory (FADL).  This case report provides insight on how veterinarian staff and laboratory personnel can clinically manage esoteric, unexplained, or post-mortum examinations.  The epidemiologic characteristics of tularemia, F. tularensis as an organism of military interest, potential laboratory management of F. tularensis, and clinical findings on a case of feline tularemia are discussed. It further raises questions as to whether or not dead animals should be treated as sentinels and be pre-screened for select agents, especially in instances of dual diagnoses.

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