A Randomized, Double-Blind Trial of Lisinopril and Losartan for the Treatment of Cardiomyopathy in Duchenne Muscular Dystrophy
Author(s) -
Hugh D. Allen,
Kevin M. Flanigan,
Philip T. Thrush,
Igor Dvorchik,
Han Yin,
Charles E. Canter,
Anne M. Connolly,
Mark D. Parrish,
Craig M. McDonald,
Elizabeth Braunlin,
Steven D. Colan,
John Day,
Basil T. Darras,
Jerry R. Mendell
Publication year - 2013
Publication title -
plos currents
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.282
H-Index - 49
ISSN - 2157-3999
DOI - 10.1371/currents.md.2cc69a1dae4be7dfe2bcb420024ea865
Subject(s) - lisinopril , medicine , duchenne muscular dystrophy , losartan , ejection fraction , dystrophin , muscular dystrophy , cardiology , cardiomyopathy , angiotensin converting enzyme , heart failure , angiotensin ii , blood pressure
This study sought to compare the effectiveness and safety of an angiotensin converting enzyme inhibitor (ACE-I) (lisinopril) vs. an angiotensin receptor blocker (ARB) (losartan) for the treatment of cardiomyopathy (CM) in boys with Duchenne muscular dystrophy (DMD).
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