
Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model
Author(s) -
Evan T. Jelly,
Zachary A. Steelman,
Adam Wax
Publication year - 2019
Publication title -
optics letters/optics index
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.524
H-Index - 272
eISSN - 1071-2763
pISSN - 0146-9592
DOI - 10.1364/ol.44.005590
Subject(s) - optical coherence tomography , articular cartilage , osteoarthritis , biomedical engineering , tomography , computer science , optics , materials science , medicine , physics , alternative medicine , pathology
There exists an unmet need for an optical coherence tomography (OCT) delivery scheme that is simple, robust, and applicable to general surgical applications. To deliver the beam in a narrow form factor, optical borescopes present an attractive potential solution. We present a method for enabling endoscopic delivery of OCT using a handheld rigid borescope adapted to a low-cost OCT engine. The system reduces the distal profile of the scanner, enabling application of the system in otherwise hard-to-access regions. The clinical potential of this design is demonstrated through real-time quantification of articular cartilage thickness, a primary biomarker of joint health during osteoarthritis. This platform has the potential to enable use of OCT for real-time feedback during arthroscopic surgery.