Open AccessUltra-fast dynamic line-field optical coherence elastography
Author(s) -
Manmohan Singh,
Alexander Schill,
Achuth Nair,
Salavat R. Aglyamov,
Irina V. Larina,
Kirill V. Larin
Publication year - 2021
Publication title -
optics letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.524
H-Index - 272
eISSN - 1071-2763
pISSN - 0146-9592
DOI - 10.1364/ol.435278
Subject(s) - supercontinuum , optical coherence tomography , optics , michelson interferometer , interferometry , coherence (philosophical gambling strategy) , spectrometer , materials science , elastography , physics , optical fiber , acoustics , ultrasound , photonic crystal fiber , quantum mechanics
In this work, we present an ultra-fast line-field optical coherence elastography system (LF-OCE) with an 11.5 MHz equivalent A-line rate. The system was composed of a line-field spectral domain optical coherence tomography system based on a supercontinuum light source, Michelson-type interferometer, and a high-speed 2D spectrometer. The system performed ultra-fast imaging of elastic waves in tissue-mimicking phantoms of various elasticities. The results corroborated well with mechanical testing. Following validation, LF-OCE measurements were made in in situ and in in vivo rabbit corneas under various conditions. The results show the capability of the system to rapidly image elastic waves in tissues.