Open AccessSpectrally dependent roll-off in visible-light optical coherence tomography
Author(s) -
Ian Rubinoff,
Brian Soetikno,
D. A. B. Miller,
Isabella Rischall,
Amani A. Fawzi,
Roman V. Kuranov,
Hao F. Zhang
Publication year - 2020
Publication title -
optics letters/optics index
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.524
H-Index - 272
eISSN - 1071-2763
pISSN - 0146-9592
DOI - 10.1364/ol.389240
Subject(s) - optical coherence tomography , spectrometer , optics , imaging spectrometer , coherence (philosophical gambling strategy) , physics , tomography , materials science , quantum mechanics
Recent development of visible-light optical coherence tomography (vis-OCT) has introduced new applications for noninvasive spectroscopic imaging. However, the measured spectra may be altered by spectrally dependent roll-off (SDR). We formulated a mathematical model for SDR that accounted for nonuniform wavenumber spacing, optical aberrations, and misalignments in the spectrometer. We simulated SDR based on this model and found strong agreement with measurements from a vis-OCT system. We verified that SDR altered spectroscopic measurements of fully oxygenated blood. We corrected these alterations by normalizing each spectrally dependent A-line by the measured SDR of the spectrometer. Our investigations of SDR are critical for informing OCT spectrometer design, alignment, and spectroscopic measurements.